Friday, September 24, 2004

Blue has Heart Disease

My dog Blue has been diagnosed with Congenitive heart falure and so he is now on a diaretic known as Furosemide.

It is a potent diuretic which inhibits the resorption of sodium, potassium, chloride, and hydrogen ion from the ascending limb of the loop of Henle - as these ions are excreted, water follows. The dose and frequency of furosemide required is dependent upon the severity of pulmonary edema present and the degree of respiratory distress. In severe, life-threatening cases, furosemide should be administered intravenously (IV) and at relatively high dosages - 4-6 mg/kg. When administered IV, furosemide’s onset of action is 5 minutes, the peak effect occurs at 30 minutes, and effects wane at 2 hours. Once CHF patients have been stabilized, furosemide is usually continued orally at maintenance dosages - 0.5 to 1.0 mg/kg SID - BID. In managing chronic cases, the clinician should find the lowest dose of furosemide that will control pulmonary edema and its attendant clinical signs including cough and respiratory distress. Side effects of furosemide may include volume depletion and prerenal azotemia, hypokalemia, and metabolic alkalosis (renal loss of hydrogen).

He is also on Enalapril, which is a vasodilator for his heart.

woof!

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